It won't mess up anything except the "Ready Status" of the various sensors, which will require a drive cycle to reset. Not an issue in non-inspection Florida. You will also lose radio presets, of course. By the way, I don't think a battery maintainer will work to prevent losing the sensor status during a battery change. Most maintainers will shut down if they don't detect battery voltage. Be careful: It's a long, heavy reach to remove and replace that battery. Don't use the fender as a fulcrum.